BOSTON, Massachusetts: Significant development work has been made by the international researchers for finding prominent areas in DNA of human body increasing risks of rheumatoid arthritis.
An international team of researchers has claimed to find more than 40 new areas in human’s DNA involved in increasing the risks of rheumatoid arthritis.
Nearly 30,000 patients were involved in the is the largest genetic study ever carried out by the researchers’ team.
The investigators believe new drugs could be developed to target these areas that could one day provide a cure for the disease.
The research team compared the DNA of arthritis patients with those without the disease and found 42 ‘faulty’ areas that were linked with the disease. The hope is that drugs can be developed to compensate for these faults.
The lead researcher Professor Robert Plenge of Harvard Medical School found that one of these areas produced a weakness that was treated by an existing drug that was developed by trial and error, rather than specifically made to correct the genetic problem.
The findings are published in the Journal Nature.
This finding, he says, shows such discoveries could be used to design new drugs.
“What this offers in the future is an opportunity to use genetics to discover new medicines for complex diseases like rheumatoid arthritis to treat or even cure the disease,” he said.